STRING: functional protein association networks

STRING: functional protein association networks

This is the evidence view. Different line colors represent the types of evidence for the association.




confidence	evidence	actions	interactive	advanced	more	less	save

Your Input:
	EBPL	emopamil binding protein-like; Does not possess sterol isomerase activity and does not bind sigma ligands (206 aa)
	SC5DL	sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like; Catalyzes a dehydrogenation to introduce C5-6 double bond into lathosterol (299 aa)
	TM7SF2	transmembrane 7 superfamily member 2; Involved in the conversion of lanosterol to cholesterol (418 aa)
	DHCR24	24-dehydrocholesterol reductase; Catalyzes the reduction of the delta-24 double bond of sterol intermediates. Protects cells from oxidative stress by reducing caspase 3 activity during apoptosis induced by oxidative stress. Also protects against amyloid-beta peptide-induced apoptosis (516 aa)
	CTNNBIP1	catenin, beta interacting protein 1; Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt signaling pathway (81 aa)
	EBP	emopamil binding protein (sterol isomerase); Catalyzes the conversion of Delta(8)-sterols to their corresponding Delta(7)-isomers (230 aa)
		(Homo sapiens)
Predicted Functional Partners:

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Info & Parameters ...

Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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interactors shown:

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additional (white) nodes

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