STRING: functional protein association networks

STRING: functional protein association networks

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	HMGB2	high-mobility group box 2; Binds preferentially single-stranded DNA and unwinds double stranded DNA (209 aa)
	HMGA1	high mobility group AT-hook 1; HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts. They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions (107 aa)
	POU3F1	POU class 3 homeobox 1; Transcription factor that binds preferentially to the recognition sequence which consists of two distinct half-sites, ('GCAT') and ('TAAT'), separated by a nonconserved spacer region of 0, 2, or 3 nucleotides. Positively regulates the genes under the control of corticotropin-releasing hormone (CRH) and CRH II promoters (By similarity) (451 aa)
	POU3F4	POU class 3 homeobox 4; Probable transcription factor which exert its primary action widely during early neural development and in a very limited set of neurons in the mature brain (361 aa)
		(Homo sapiens)
Predicted Functional Partners:

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Info & Parameters ...

Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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additional (white) nodes

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