STRING: functional protein association networks

STRING: functional protein association networks

This is the evidence view. Different line colors represent the types of evidence for the association.




confidence	evidence	actions	interactive	advanced	more	less	save

Your Input:
	MMP8	matrix metallopeptidase 8 (neutrophil collagenase); Can degrade fibrillar type I, II, and III collagens (467 aa)
	UMOD	uromodulin; Not known. May play a role in regulating the circulating activity of cytokines as it binds to IL-1, IL-2 and TNF with high affinity (640 aa)
	LTA	lymphotoxin alpha (TNF superfamily, member 1); Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo (205 aa)
	ENSG00000226979	Lymphotoxin-alpha Precursor (LT-alpha)(TNF-beta)(Tumor necrosis factor ligand superfamily member 1) (205 aa)
		(Homo sapiens)
Predicted Functional Partners:

Views:

Info & Parameters ...

Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

required confidence (score):

interactors shown:

or custom value:

custom limit:

additional (white) nodes

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