thrombopoietin; Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets (353 aa)
myeloproliferative leukemia virus oncogene; Receptor for thrombopoietin. May represent a regulatory molecule specific for TPO-R-dependent immune responses (635 aa)